Musculoskeletal and Anti Inflammatory Medications

Musculoskeletal and Anti-Inflammatory Medications Assignment Pharmacology

  1. Acute painful musculoskeletal conditions are treated with a combination of relaxants, rest, physical therapy and mild analgesics. Skeletal muscle relaxant drugs used to treat these conditions are diazepam (Valium) and methocarbanol (Robaxin).
  2. Dantrolene is used in the treatment of muscle spasticity resulting from multiple sclerosis or cerebral palsy conditions. It is ineffective in the treatment of amyotrophic lateral sclerosis (ALS).
  3. Who may administer neuromuscular blocking agents?

Neuromuscular blocking agents are administered only by anesthesiologists or trained personnel skilled in intubation and cardiopulmonary resuscitation.

  1. What three things should be included in patient education about muscle relaxants?
    1. i. Potential side effects of drowsiness, dizziness, weakness, tremor, blurred vision, hypotension, respiratory distress, GI distress, etc while driving.
    2. ii. Avoidance of other CNS depressants (alcohol, antihistamines, tranquilizers, etc) concomitantly.
    3. iii. Taking medication only as long as absolutely necessary and taking caution regarding prolonged use, which could cause physical or psychological dependence and withdrawal symptoms.
    4. Anti-inflammatory drugs include NSAIDS and Cox 2 inhibitors. What group of individuals is particularly susceptible to side effects of NSAIDS?

Older adults are particularly susceptible to side effects of NSAIDS, because this group of individuals has lower metabolic rates and often times preexisting complications.

  1. Which of the NSAIDS is known for its analgesic, anti-inflammatory and anti-pyretic effects?

The salicylates (such as aspirin) are NSAIDS which are known for its analgesic, anti-inflammatory and anti-pyretic effects.

  1. NSAIDS are known for causing ulceration in the stomach. How would the nurse know if the client were developing an ulcer?

Nurse has to carefully monitor the patients taking NSAIDS for its side effect of stomach ulceration by observing and assessing the signs and symptoms of problems in GI, which could include blood in stool, urine and vomit, and feeling weak.

  1. Colchicine is the drug of choice for acute gouty arthritis.
  2. What is the rational for clients being told that when taking Actonel and/or Fosamax that they should take the pill first thing in the morning and then wait at least 30 minutes before eating?

Bioavailability of Actonel and Fosamax is reduced when there is food in our digestive system and results in decreased therapeutic effect. Our digestive system is relatively empty in the morning, so taking these medication works during that time is more effective.

10. How should calcitonin be stored?

Store the unopened calcitonin bottle in refrigerator, and once the pump has been activated, store it in a room temperature in an upright position.


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